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Common interactions with calcineurin inhibitors

Common interactions with calcineurin inhibitors The calcineurin inhibitors (CNIs), tacrolimus and ciclosporin, both metabolised by the enzyme CYP3A4 and P-glycoprotein, will be the first-line medications that are immunosuppressant to stop organ rejection 15. Drug–drug interactions can cause changes that are significant bloodstream plasma amounts and mainly happen when medicines…

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